Toa Payoh
Vets Clinical Research Making veterinary surgery alive
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Injectable Anaesthesia in the dog, cat, guinea pig and
rabbit
Dr
Sing Kong Yuen, BVMS (Glasgow), MRCVS First recorded: 5 April, 2011
14 September, 2015
Injectable anaesthesia in the healthy dog and
cat
in one syringe. Calculated dosage for healthy animals
Weight
Domitor
Ketamine
10kg healthy
0.4 ml IV
0.5 ml IV
Dogs less than 5
years old, in good health
Domitor 5-40ug/kg = 0.005mg/kg-0.04mg/kg
Ketamine 2-5mg/kg
Heart-diseased dogs - Do not use domitor+ketamine
Old dog - Use less domitor
Injectable anaesthesia in the healthy dog and catin one syringe. Calculated dosage for healthy animals
Weight
Diazepam
Ketamine
10kg healthy
dog
0.8 ml* IV
0.5 ml IV
Diazepam 0.1-0.4 mg/kg.
* is based on maximal dose
Ketamine 2-5mg/kg
Heart-diseased dogs - give 50% + isoflurane gas top up
Spay healthy dogs - give higher dose in the higher range. No
need isoflurane gas top up.
Weight
Xylazine
Ketamine
2-3
kg healthy cat
0.1ml
0.4
ml
3-4
kg healthy cat
0.15ml
0.6
ml
4-5
kg healthy cat
0.2ml
0.8ml
I find the above dosage IM effective and safe for
spaying and neutering to be done in less than 20 minutes. Top up
with isoflurane if necessary. I know of a vet who routinely use
Reverzine to reverse the xylazine-induced sedation. It must be
given by IV only.
Rabbit & Guinea Pig.
Use Subcutaneous inj onlyin one syringe
Xylazine + Ketamine IM can also be used in rabbit
anaesthesia.
CASE STUDIES OF 3 DOGS
USING DOMITOR+KETAMINE
Weight
Domitor
Calculated
Ketamine
Calculated
Domitor Given
Ketamine Given
10kg healthy
0.4 ml IV
0.5 ml IV
Case 1
Fox Terrier, 1 year, 9.3kg spay
0.37 ml IV
0.47 ml IV
0.2 ml IV
0.3 ml IV
Young, healthy
Needs isoflurane
maintenance as dosage is below calculated dose. No problems.
When antisedan 0.2 ml IM is given, wakes up alert but limbs
are rigid. Can't stand up till atropine 0.1 ml IV is given.
Case 2
Shih Tzu, F, 7 years, 8.1 kg
0.32 ml IV
0.41 ml IV
0.1 ml IV
0.4ml IV
Old age, be careful
Needs isoflurane maintenance as dosage is below
calculated dose. No problems. Dental scaling. When antisedan
0.1 ml IV is given, no cries. Just wakes up as if from a nap.
Case 3
Maltese, F, 8 years, 4.3 kg
0.17 ml IV
0.22 ml IV
0.1ml IV
0.2ml IV
Old age, be careful
No need isoflurane
gas as dosage is close to calculated dose. 6 teeth extracted.
No problem. When antisedan 0.1 ml IV is given, cries in pain.
Given tolfedine injection. Stops crying.
Dosage for the two old dogs - shih tzu
and maltese
Fox Terrier,
1 year, Spayed. Rigid limbs
after giving antisedan
to wake up the dog early
In conclusion, domitor and ketamine
are synergistic and their combined use will be safer if injectable
anaesthetics are required and no isoflurane gas is available. For
healthy dogs, use the calculated dosage given above.
For
heart-diseased dogs, use diazepam + ketamine at 50% of calculated
dose and give isoflurane gas top up. Do NOT use domitor + ketamine
is heart-diseased dogs.
For dogs over 7 years, use 50% of calculated dose for healthy dogs
and top up with isoflurane gas if necessary.
BE KIND TO
HAMSTERS. Get their tumours
removed when they are much
smaller. More case studies, goto:
Hamsters